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Summary
Wolverine ’s healing gene is perhaps his most utilitarian and most iconic power . much any combat injury he suffers , from gunshot wound and stabbings to devastating explosions and immense anguish , Wolverine can recover from . However , that is n’t to say he ’s unbeatable by any means , as there are a few time in Marvel canyon thatWolverine ’s healing factorhasn’t been able to write him .
While most enemies do n’t have the strength , skills , or intelligence operation to do so , there are some who have managed to get around Wolverine ’s healing factor and take theX - Menhero down . Here are the Top 12 Marvel character who formally beat ( or could beat ) Wolverine ’s healing factor .
12The Punisher
Frank Castle aka the Punisher has never encounter someone he could n’t pop , and the fictional character show as much in the storylinePunisher Kills the Marvel Universeby Garth Ennis and Doug Braithwaite . While literally everyone is on the Punisher ’s smash - list , it was clear from the start that Wolverine would be one of the toilsome to take down - though not impossible . The Punisher beat Wolverine ’s healing factor by prod him in the neck opening to throw him off - guard , and then tossing him into a maximum potential author . The subsequent electrocution is so withering , that Logan ’s cells do n’t have the chance to regenerate , killing him permanently .
11Deadpool
Like the Punisher , Deadpool also decided to kill the intact Marvel Universe during one of his off - shoot storylines . InDeadpool Kills the Marvel Universeby Cullen Bunn and Kaare Andrews , the fact that Deadpool knows he ’s a fabricated character causes him to become a deranged mass manslayer , killing everyone in Marvel Comics because he ’s ‘ saving ’ them from the ageless torture of their sham lives . Naturally , that included Wolverine . Deadpool killed Wolverine with a sword that ’s made from carbonadium , which has the ability to slow Wolverine ’s healing factor exponentially . Deadpool stabbed Wolverine with this sword , invalidate his bring around element and killing him in mere moments .
10Ultimate Mad Thinker
InUltimate X - Men / fantastical Four#1 by Mike Carey and Pasqual Ferry , Wolverine goes toe - to - toe with the Ultimate Universe ’s adaptation of the Mad Thinker aka Rhona Burchill . If fan think Earth-616 ’s evil genius was bad , they have n’t experience the unfeigned menacing brilliance of Earth-1610 ’s . With the power to descend up with maniacal plots in a fraction of a second , it did n’t take long for theMad Thinker to picture out how to take Wolverine down . Rhona created a retrovirus that weakened Wolverine ’s healing factor by assail his cell every 12 second , making Wolverine easy to defeat , as his torso could n’t repair any wrong to it at that rate .
9X-23
While Laura Kinney has now taken up the sobriquet of Wolverine herself , there was a time when she was little more than a living weapon make out only as X-23 - and one of her fair game was Logan . InX-23 : Target X#6 by Christopher Yost , Craig Kyle , and Mike Choi , Laura is stalking Wolverine with the purport to kill him . When the two of them finally fight , X-23 hacks and slashes at Wolverine with her claw , and she shoves fistful of stain into every bloody opening she constitute in his cutis . By contribute dirt to the candid wounds , X-23 hold back Wolverine ’s peel from compensate itself . This was a temporary measure that had to be repeated over and over again along with increasingly savage attacks to have any kind of lasting impact . Though no matter how simple and unawares - lived it was , X-23 pulled off what few mass have and actually exhaust Wolverine ’s healing factor .
8Hulk
X-23 and the Mad Thinker used their brain to beat Wolverine ’s healing gene , whereas Hulk simply used his world - destruct strong point . InWorld War Hulk : X - Menby Christos N. Gage and Andrea Di Vito , the Worldbreaker Hulk is fighting every member of the X - gentleman’s gentleman to get to Professor X , as he ’s in the middle of exact payback upon the Illuminati for sending him off - macrocosm , and then allegedly bolt down the family he determine . However , the X - human were n’t going to let that happen , especially Logan . Unfortunately , this edition of the Hulk was much more focussed and intelligent than other ‘ Hulk ’ persona ’s within Banner ’s fractured psyche , and he knew precisely where to hit Wolverine to render his healing ingredient utterly useless . By repeatedly punch him substantial in the head , Hulk was causing Wolverine ’s brain to rattle around in his skulland hit into the adamantium that coat it . After a few collision , Wolverine was down for the count , with a level of brain damage that even he ask an wide amount of time to recover from .
7Ultron
Ultron is a villain with near - limitless potential drop in term of how deadly he can be , and in one What If … ? account , he test it on Wolverine . In theWhat If ? Astonishing X - Men#1 story titled “ What If Danger Became A Bride Of Ultron ? ” by Matteo Casali and Mike Getty , Ultron weaponizes a gimmick that ’s been underutilized in the main Marvel canon for decade : the Encephalo - Beam . This weapon system allows Ultron to enroll the minds of his victim . Ultron can apply it to control citizenry , wipe their memories , or just melt their brains . When he used it against Wolverine , Ultron reduced Wolverine ’s brain to cornmeal mush in a matter of seconds , giving Logan ’s healing component no time to even read what was happening , allow alone do anything to prevent it .
6Blink
In theAge of Apocalypsetimeline ( mainly featured in theAstonishing X - Mentie - in miniseries by Scott Lobdell and Joe Madureira ) , Blink is a mutant member of what became of the X - Men , using her power to create portals to combat En Sabah Nur and fight his planet - destroying agenda . The furthest placement Blink has canonically been able to make a portal to is the moon , meaning she could easily open up a hepatic portal vein underneath Wolverine ’s effort and teleport him to any area of space in between Earth and the moon and give him to die in the vacuum . While the two have never fought , Blink ’s power makes her one of the greatest threat to Logan should he ever regain himself on her risky side , as she can end him in the blink of an center in a way that makes his healing factor entirely irrelevant .
5“Death of Wolverine” Hivemind Virus
Introduced inWolverineVol . 5 and bring to its naturally grim conclusion in the miniseriesDeath of Wolverineby Charles Soule and Steve McNiven , Wolverine loses his healing factor after he ’s taint by a virus grow in the microverse . This computer virus was sentient , a hivemind - like organism that want to plunge the intact world , and even beyond . Wolverine helped prevent that from happening , but in doing so , he lost his healing constituent . For nearly two full volumes of Wolverine comics , Logan is hunt by his expectant enemies , as they ultimately had a probability at killing him once and for all . In the remainder , Wolverine does buy the farm , and while the microverse hivemind does n’t deliver the last coke , it would n’t have happened if the virus did n’t rob Logan of his healing factor .
4Doctor Nemesis
During Marvel Comics ’ “ Wolverine vs the X - Men ” arc by Jason Aaron , Daniel Acuna , and Corey Petit , Wolverine is possessed by demon from the Red Right Hand , forcing him to turn against his fellow X - Men appendage . To stop him , Doctor Nemesis shoots Logan with a dart gun turn back some of the earthly concern ’s deadliest disease , including bubonic plague , mouth cancer , and flesh - eating bacterium . After a few of those dart , Wolverine was too meddlesome emesis and slash to fight , as the illnesses overloaded his bring around factor .
3Nimrod
InInferno#1 by Jonathan Hickman and Valerio Schiti , the go - work force are battling their enceinte enemy in the history of Marvel Comics : the Sentinels . Specifically , they ’re trying to take down Nimrod and save the planet from the malign organization have it away as Orchis . With the X - Men ’s resurrection ability , they can throw everything they have at Nimrod during every face-off without fearfulness of death , as they ’ll be back with unexampled , resurrected configuration in no time . In Wolverine ’s display case , that meant he had to experience the same horrific destruction over and over again . As shown in this issue , Nimrod would sear the physique from Wolverine ’s adamantium pearl , cooking his head inside his skull , and reducing Logan to a living - sized trophy . This was an homage to Wolverine ’s famed destruction inDays of Future Pastby the hand of a Sentinel , though Nimrod did it with much more authority . This villain made killing Wolverine a legitimate hobby of his , and Logan ’s healing ingredient was of small to no worry , as Nimrod was able to vaporize him faster than he could mend .